Colon Targeted Curcumin Delivery Using Guar Gum
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چکیده
منابع مشابه
Colon Targeted Guar Gum Compression Coated Tablets of Flurbiprofen: Formulation, Development, and Pharmacokinetics
The rationale of the present study is to formulate flurbiprofen colon targeted compression coated tablets using guar gum to improve the therapeutic efficacy by increasing drug levels in colon, and also to reduce the side effects in upper gastrointestinal tract. Direct compression method was used to prepare flurbiprofen core tablets, and they were compression coated with guar gum. Then the table...
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متن کاملInvestigations on chitosan-carboxymethyl guar gum complexes interpolymer complexes for colon delivery of fluticasone
Gurpreet Kaur Ranbaxy Research Labs, Gurgaon, India Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala-147002, India Tel: 919814724622 Fax +91-(0175)-3046255 Email: [email protected] Abstract The present study was designed to formulate colon release tablets of fluticasone by employing cross linked chitosan (CH) and carboxymethyl guar gum (CMG) interpolymer comp...
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PURPOSE The present investigation is to study the influence of metronidazole and tinidazole on the usefulness of guar gum, a colon-specific drug carrier based on the metabolic activity of colonic bacteria, using matrix tablets of albendazole (containing 20% of guar gum) as a model formulation. METHODS The matrix tablets of albendazole were subjected to in vitro drug release studies in simulat...
متن کاملDevelopment of pH Sensitive Nanoparticles for Intestinal Drug Delivery Using Chemically Modified Guar Gum Co-Polymer
The aim of the research work was to chemically modify guar gum(GG) as a pH sensitive co-polymer and formulating intestinal targeting ESO nanoparticles (NPs) using the synthesized co-polymer. Poly acrylamide-grafted-guar gum (PAAm-g-GG) co-polymer was synthesized by free radical polymerization. Chemical modification of PAAm-g-GG by alkaline hydrolysis results in formation of a pH-sensitive co-po...
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ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2010
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x1000500621